Enzyme Technical Association Documents

The ETA produces timely documents and position papers to help our members, regulators, customers, and key stakeholders have access to valuable information associated with enzyme use in various industries. The document library is updated on a regular basis by the ETA committees.

General Enzyme Information

Industrial Biotechnology Journal Publication: “The Generally Recognized As Safe (GRAS) Process for Industrial Microbial Enzymes”

Enzymes – A Primer on Use and Benefits

ETA Position Papers

ETA Position on Microbially Derived Enzymes Used as Food Processing Aids and Food Allergen Labeling Under FALCPA as it Applies to Fermentation Media Raw Materials

ETA responds to recent Food and Chemical Toxicology article, ”GRAS from the ground up: Review of the Interim Pilot Program for GRAS notification” by Hanlon et al., 2017

ETA Comments to Non-GMO Project Revised Standards

29-CFR-1910.1200 & ETA GHS Guidance for Enzymes

ETA Position Paper on the GRAS Status of Beta Amylase from Ungerminated Barley

ETA Position Statement on the Safety of Enzymes Used in the Manufacture of Ethanol from Grains with Use of Co-Products as Animal Feed

ETA Position Paper Biotechnology, Enzymes and Allergies

Enzymes in Technical Applications 

Enzymes for the Cleaning Industry

Food, Feed and Dietary Supplements

GRAS – Generally Recognized as Safe

ETA Panel at IFT16 on Generally Recognized as Safety (GRAS) Concept

(IFT 16 Presentation): ETA Presentation at IFT 16 on Generally Recognized as Safety (GRAS) Concept

ETA Standard Manufacturing Process for Fermentation-based Enzymes Used in Food

ETA Comment Letter – CFIA Permissible Claims

ETA – CRN – Best Practices Guide for Enzymes as Dietary Supplements

Distillers’ Grains, PowerPoint Presentation by FDA CVM at RFA National Ethanol Conference, February 2008

ETA Transglutaminase Letter to FSIS

Enzyme Safety Statement Ethanol Production and Distillers Grains

An Industry-Sponsored Survey on Genotoxicity and Oral Toxicity Study Data from Enzymes Produced Using Protein Engineering

Orally Administered Enzyme Food Supplement Safety Overview

Health Canada Enzyme AbLS pdfs (English)

Communications with FDA concerning “natural” and HFCS

Letter to FDA on natural and HFCS

FDA response to CFA re HFCS

FDA response on HFCS

Safe Handling of Enzymes

ETA Presentation at BIO World Congress Conference Discussing Enzyme Safety

Working Safely With Enzymes – English

Safe Handling of Enzymes, Textile Chemist and Colorist & American Dyestuff Reporter, Vol. 32, No. 1, January 2000

AISE Allegren Guidance Document 8 February 2002

ETA and AMFEP Guideline on Consumer Risk Assessments for Enzyme-Containing Personal Care Products and Cosmetics